Are There Any Side Effects of Ivermectin?

Ivermectin 6 mg tablet dose is a widely used antiparasitic medication that has proven effective in treating a variety of infections caused by parasitic worms, lice, and mites. Initially developed for veterinary use, it quickly became a human medicine, especially for diseases like onchocerciasis (river blindness) and strongyloidiasis. While ivermectin is generally considered safe when used correctly, like all medications, it can have side effects. Understanding these side effects can help patients and caregivers use it responsibly and recognize when medical attention is needed.

This article explores the common, mild, and rare but serious side effects of ivermectin, who is more at risk, and how to reduce the chances of adverse effects.

What Is Ivermectin Used For?

Before diving into the side effects, it’s important to understand why ivermectin is prescribed. It’s commonly used to treat:

• Strongyloidiasis (intestinal roundworm infection)
  
  

• Onchocerciasis (river blindness)
  
  

• Scabies
  
  

• Head lice
  
  

• Lymphatic filariasis
  
  

• Other parasitic worm infections
  
  

Ivermectin works by paralyzing and killing parasites. It's available in oral tablets, topical creams, and lotion forms.

Common Side Effects of Ivermectin

Most people tolerate ivermectin well, especially when taken as a single dose or short course. However, some mild side effects may occur, particularly within the first few days of treatment.

a. Gastrointestinal Side Effects

These are the most frequently reported:

• Nausea
  
  

• Vomiting
  
  

• Diarrhea
  
  

• Abdominal pain
  
  

• Loss of appetite
  
  

These symptoms are usually short-lived and manageable without medical intervention.

b. Skin Reactions

When ivermectin is used to treat parasitic skin infections like scabies or lice, some users may experience:

• Itching
  
  

• Rash
  
  

• Dry skin
  
  

• Mild swelling or redness
  
  

These symptoms can occur as the parasites die off, and they may temporarily worsen before improving.

c. Neurological Symptoms (Mild)

Though rare in low-risk patients, some people may experience:

• Dizziness
  
  

• Drowsiness
  
  

• Headache
  
  

• Muscle aches
  
  

These side effects usually subside as the body adjusts to the medication.

Side Effects Due to Parasite Die-Off (Mazzotti Reaction)

When ivermectin is used to treat infections like onchocerciasis, patients may experience a Mazzotti reaction. This occurs due to the body’s immune response to dying parasites, not the drug itself.

Symptoms of Mazzotti Reaction:

• Fever
  
  

• Chills
  
  

• Swollen lymph nodes
  
  

• Rapid heartbeat
  
  

• Skin rash or itching
  
  

• Joint or muscle pain
  
  

• Low blood pressure
  
  

• Eye inflammation
  
  

This reaction can range from mild to severe and is more common in people with a heavy parasitic load. Medical supervision is essential in such cases, and doctors may prescribe corticosteroids to manage symptoms.

Rare but Serious Side Effects of Ivermectin

While uncommon, serious side effects can occur, particularly if the drug is taken inappropriately or at very high doses.

a. Neurological Side Effects

• Confusion or disorientation
  
  

• Tremors
  
  

• Seizures
  
  

• Difficulty walking
  
  

• Visual disturbances (blurred or double vision)
  
  

These symptoms may indicate ivermectin is affecting the central nervous system. This is more likely in individuals with a compromised blood-brain barrier or those taking interacting medications.

b. Liver Toxicity

• Elevated liver enzymes
  
  

• Yellowing of the skin or eyes (jaundice)
  
  

• Fatigue
  
  

• Dark-colored urine
  
  

Liver damage from ivermectin is rare, but regular monitoring may be recommended in long-term or repeated use.

c. Allergic Reactions

Some people may be allergic to ivermectin or its inactive ingredients.

Signs of a serious allergic reaction include:

• Difficulty breathing
  
  

• Swelling of face, lips, or throat
  
  

• Hives or severe rash
  
  

• Anaphylaxis (a medical emergency)
  
  

Seek immediate medical help if these symptoms appear.

 Ivermectin in Children and Elderly Patients

Children:

• Ivermectin is generally not recommended for children weighing under 15 kg (around 33 pounds).
  
  

• In approved doses, it is considered safe for older children.
  
  

Elderly:

• Older adults may be more susceptible to neurological side effects, especially if they have liver problems or are on multiple medications.
  
  

• Careful dosage and monitoring are advised.
  
  

Ivermectin and Drug Interactions

Ivermectin can interact with other medications, increasing the risk of side effects. Inform your doctor if you're taking:

• Blood thinners (like warfarin)
  
  

• Anti-seizure medications
  
  

• HIV/AIDS medications (like efavirenz)
  
  

• Other antiparasitic or antifungal drugs
  
  

Combining these with ivermectin may raise drug levels in the body, potentially causing toxicity.

Precautions to Take Before Using Ivermectin

To reduce the risk of side effects, tell your healthcare provider if you:

• Have liver or kidney disease
  
  

• Have a history of neurological disorders (seizures, meningitis)
  
  

• Are pregnant or breastfeeding
  
  

• Are taking other medications
  
  

• Have a weakened immune system
  
  

They may adjust the dose or monitor you closely during treatment.

Ivermectin Misuse and Toxicity Risks

In recent years, ivermectin gained attention for off-label use, especially during the COVID-19 pandemic. This led to reports of ivermectin poisoning, mostly from people self-medicating with veterinary formulations meant for animals.

Risks of overdose include:

• Vomiting and severe diarrhea
  
  

• Hypotension (low blood pressure)
  
  

• Vision problems
  
  

• Seizures
  
  

• Coma
  
  

Important: Never take ivermectin meant for animals. Always use human-approved forms under medical supervision.

How to Manage Side Effects of Ivermectin

Mild Side Effects:

• Stay hydrated and rest.
  
  

• Eat light meals to ease gastrointestinal symptoms.
  
  

• Use antihistamines for itching or mild allergic reactions (only with a doctor’s approval).
  
  

Moderate to Severe Side Effects:

• Contact your healthcare provider immediately.
  
  

• Go to the emergency room if you experience seizures, chest pain, severe rash, or difficulty breathing.
  
  

Summary: Should You Be Worried About Ivermectin Side Effects?

When prescribed by a medical professional and taken as directed, ivermectin is safe and effective for most people. Its side effects are usually mild and temporary, especially for single-dose treatments. However, serious side effects can occur, particularly in those with preexisting conditions, heavy parasite loads, or those who misuse the drug. For quality and convenience, purchase ivermectin online from DosePharmacy today.

To minimize risks:

• Follow dosage instructions carefully.
  
  

• Never self-medicate or use veterinary ivermectin.
  
  

• Inform your doctor of any underlying health issues or medications.
  
  

Final Thoughts

Ivermectin has helped millions around the world combat parasitic diseases with a high success rate. While it can cause side effects, they are mostly manageable and rare when used properly. With careful use and medical supervision, the benefits of ivermectin often far outweigh its risks. If you're prescribed ivermectin, stay informed, follow your healthcare provider's guidance, and report any unusual symptoms promptly.